| 08/18/2022 | vs Oakland | L | 0-1 | 0-1-0, 0-0-0 | 0-0-0 | 286 | Â |
| 08/25/2022 | at UIC | W | 1-0 | 1-1-0, 0-0-0 | 0-0-0 | 210 | Susie Soderstrom (1) (Grace Phillpotts)
|
| 08/28/2022 | at Iowa | L | 0-4 | 1-2-0, 0-0-0 | 0-0-0 | 700 | Â |
| 09/01/2022 | vs Northwestern | L | 1-3 | 1-3-0, 0-0-0 | 0-0-0 | 339 | Freya Jupp (1) (Susie Soderstrom)
|
| 09/08/2022 | at Loyola Chicago | L | 1-2 | 1-4-0, 0-0-0 | 0-0-0 | 385 | Beth Smyth (1)
|
| 09/11/2022 | vs Stanford | L | 1-3 | 1-5-0, 0-0-0 | 0-0-0 | 425 | Katie Godden (1) (Bella Hanisch)
|
| 09/15/2022 | vs Lindenwood | W | 3-1 | 2-5-0, 0-0-0 | 0-0-0 | 265 | Sydney Parker (2) (Katie Godden)
Susie Soderstrom (2) (Katie Godden)
Sydney Parker (2) (Grace Phillpotts)
|
| 09/22/2022 | vs Marquette | L | 2-3 | 2-6-0, 0-1-0 | 0-1-0 | 303 | Katie Godden (2) (Kristin Boos)
Kristin Boos (0)
|
| 9/25/2022 | at Xavier | L | 1-2 | 2-7-0; 0-2-0 | | 561 | Soderstrom, Susie (3) (Godden, Katie)
|
| 10/02/2022 | vs Georgetown | L | 0-1 | 2-8-0, 0-3-0 | 0-3-0 | 387 | Â |
| 10/06/2022 | at Providence | L | 1-2 | 2-9-0, 0-4-0 | 0-4-0 | 384 | Katie Godden (3) (Ebba Costow)
|
| 10/09/2022 | vs Butler | L | 1-2 | 2-10-0, 0-5-0 | 0-5-0 | 285 | Katie Godden (4)
|
| 10/13/2022 | at UConn | L | 1-3 | 2-11-0, 0-6-0 | 0-6-0 | 878 | Katie Godden (5) (Grace Phillpotts)
|
| 10/16/2022 | vs Seton Hall | W | 2-0 | 3-11-0, 1-6-0 | 1-6-0 | 200 | Katie Godden (6)
Susie Soderstrom (4) (Freya Jupp)
|
| 10/20/2022 | at Creighton | T | 1-1 | 3-11-1, 1-6-1 | 1-6-1 | 463 | Beth Smyth (2) (Grace Phillpotts)
|
| 10/23/2022 | at Villanova | L | 1-2 | 3-12-1, 1-7-1 | 1-7-1 | 347 | Katie Godden (6)
|
